Insulin-Like Peptide Signaling in Mosquitoes: The Road Behind and the Road Ahead

Epigenetics of Host–Pathogen Interactions: The Road Ahead and the Road Behind

A growing body of evidence points towards epigenetic mechanisms being responsible for a wide range of biological phenomena, from the plasticity of plant growth and development to the nutritional control of caste determination in honeybees and the etiology of human disease (e.g., cancer). With the (partial) elucidation of the molecular basis of epigenetic variation and the heritability of certai...

The road ahead.

The recent events dedicated to eHealth, such as eHealth 2003 and eHealth 2004 Ministerial conferences and exhibition, demonstrated clearly that a critical mass of users is being created who already use eHealth services and applications. Citizens, patients and health professionals are experiencing growing benefits from the use of eHealth applications which can increase citizen information, incre...

Cancer: The Road Ahead

Fighting cancer has been the life mission for generations of biologists and clinicians, and to this effort we dedicate this issue of Cell. This reviews issue highlights the converging paths in cancer research that are enabling changes in clinical treatment and removing obstacles between patients in need and access to effective care. Empowered by these breakthroughs, it is possible to imagine ma...

The road ahead.

I describe the surrounding landscape on the road to the CERN Large Hadron Collider. I revisit the milestones of hadron-collider physics, and from them draw lessons for the future. I recall the primary motivation for the journey — understanding the mechanism of electroweak symmetry breaking — and speculate that even greater discoveries may await us. I review the physics that we know beyond the s...

The Road Ahead